Endocrine Abstracts

It is a real honour to be named Outstanding Clinical Practitioner by the Society for Endocrinology, especially as I am sharing this with my award twin, Professor Kristien Boelaert. For my presentation I will talk about aspects described in the nomination and discuss how improving patient care is at the heart of all we do. This can be achieved at an individual patient level, organisational level, and a national systems level. I will describe work around the NHS steroid emergenc...

During this session I will discuss some ways of approaching requests for interviews by the media. The media can be main stream media such a television or radio, social media such as Twitter or web based journals. It can be daunting to consider having your views for all to see or hear, however there are many reasons to engage with the media. I will discuss some strategies on how to react to requests for information and offer some suggestions on how to approach interviews and me...

During this session I will discuss some ways of approaching requests for interviews by the media. The media can be main stream media such a television or radio, social media such as Twitter or web based journals. It can be daunting to consider having your views for all to see or hear, however there are many reasons to engage with the media. I will discuss some strategies on how to react to requests for information and offer some suggestions on how to approach interviews and me...

Multidisciplinary working is key to working as an endocrinologist. MDTs can be formal, such as in an oncology context, or a looser working arrangement of health care professional across different specialties and roles providing care to patients, often with multisystem or rare endocrine conditions. They can range from an MDT with no patients present, to a multidisciplinary or joint clinic. I will discuss some different models of multidisciplinary working and ideas on how to dev...

An 82 year old lady was admitted with acute stroke on 3/1/18, confirmed on MRI. She was found to be in AF and had thyroid function tests checked on 4/1/2018, with TSH 0.01 (0.27–4.20) mIU/l and FT4 52.8 (12.0–22.0) nmol/l. She was commenced on Carbimazole 20 mg OD. TPO and TSH-receptor antibodies were both negative. An ultrasound scan confirmed a normal thyroid without any features of Grave’s disease or thyroid nodules. Clopidogrel 75 mg OD and Atorvastatin 40 m...

36F from Hungary with a h/o Graves disease in the past which was in remission since 2017 presented to ED at UCLH with a fast heart rate and acute weight loss. Feb 2020 presented with fast heart rate and FT4 84.9, TSH < 0.01. TPO Negative, TRAB raised at 6.5. Patient was commenced on 20 mg carbimazole and 20 mg TDS propranolol, referred to endocrine clinic. Patient missed her appointment in the endocrine clinic as she was in Hungary during the pandemic. June 2020: 15 weeks ...

Case 1: A 73-year-old woman underwent two separate major abdominal surgeries, one month apart, for the management of ovarian endometrioid adenocarcinoma. She had hypotensive crises about 30 minutes into each of the procedures, requiring metaraminol and noradrenaline infusions. Cortisol levels post-surgeries were 99 nmol/l and 23 nmol/l, respectively. Further questioning revealed exogenous steroid use, including high dose inhaled steroids (Fostair-800mcg/daily) and IM steroid i...

Objective: To study the effect of alemtuzumab used in Reduced Intensity Conditioning prior to hematopoietic stem cell transplant (HSCT) on thyroid function.Methods: This retrospective case review of 13 patients (9 male, 4 female) who underwent HSCT and had alemtuzumab based conditioning regimen. 5 patients had Acute lymphoblastic leukaemia, 3 severe a plastic anaemia, 1 acute myeloid leukaemia, 1 congenital bone marrow failure, 1 chronic granulomatous di...

A 21 years old male, diagnosed with ALL in 2003 (aged 9), completed treatment in June 2009 (aged 15). Chemotherapeutic agents included doxorubicin, daunorubicin, cytarabine, mercaptopurine, methotrexate, asparaginase, vincristine, dexamethasone (7 mg for 3.5 years). He didn’t receive any cranial irradiation. He underwent endocrine assessment aged 15 because of delayed puberty and had testosterone replacement for 4 years (September 2012 till January 2016). He also had hist...

Case history: A 22-year-old woman presented with a week’s history of abdominal pain and constipation. further history revealed episodes of tachycardia during childhood but no cause at that time was identified. On examination she had a sinus tachycardia, her abdomen was mildly tender and the rest of her clinical examination was completely unremarkable, including blood pressure, and there were no clinical findings consistent with Addisonian crisis.Inv...